Plasmodium Experimental Genetics Course

12 – 18 May 2019, Wellcome Genome Campus, UK

Learn the latest experimental approaches for generating genetic mutations in human malaria parasites

This laboratory-based Advanced Course will give participants a working knowledge of, and practical experience in, cutting-edge Plasmodium experimental genetics techniques, from designing gene targeting vectors and creating transgenic parasites to genotyping and phenotyping the resulting strains.

The goal is to benefit the participants’ own research careers by exposing them to state-of-the-art experimental methods, while discussing the advantages and limitations of each approach. The course is targeted to early-career stage malaria scientists who are looking to establish and use Plasmodium transfection technology at their host institutes.

The week-long residential programme will cover experimental approaches to generating genetic mutations in the human malaria parasites Plasmodium falciparum and Plasmodium knowlesi. The course is hands-on and attendees will learn how to generate gene targeting constructs with a particular focus on CRISPR-Cas9 experimental design. Participants will also perform different transfection approaches, undertake practical exercises in genotyping of modified parasites, and both observe and learn advanced molecular phenotyping approaches including drug response assays and flow cytometry. Experimental genetic approaches in other malaria parasites including the rodent malaria model Plasmodium berghei will also be discussed.

The laboratory-based programme will be complemented by specific lectures in cutting-edge areas presented by a panel of distinguished guest speakers.

For more information, visit this link

Fourth Vector-Borne Diseases in the UK Biennial Meeting

The fourth meeting on VECTOR-BORNE DISEASES IN THE UK will be held on the 3rd and 4th December, 2018 at the John Innes Centre (JIC), Norwich Research Park, and an informal dinner for delegates on the night of 3rd December. This meeting is generously supported through the Vector Biology and Climate Modelling Theme of the NIHR Health Protection Research Unit in Emerging and Zoonotic Infections at the University of Liverpool, the Plant Health Institute Strategic Programme at JIC, Defra, Oxford Biosystems, GARNet, BBSRC and SESVanderHave.

As before, the purpose of the meeting is to bring together members of the major UK research groups who have an interest in vectors or vector-borne diseases which could be a threat to the UK, groups with wider but related areas of interest, members of key UK Government Departments and their Agencies, and representatives of European organisations with an interest in this topic. It is intended that the meeting will not only provide a valuable forum for researchers to meet and exchange information and ideas, but also assist UK Government Departments and their Agencies to assess accurately the risks posed by both new and emerging disease agents, set policies which mitigate these risks and avoid activities and policies which increase them.

As with the previous meetings, we have invited a number of leading researchers to speak, and there will also be an opportunity for delegates to present their work.  All delegates will be invited to submit a short abstract of their work and from these the meeting organisers will select a limited number of oral presentations.  There will be facilities provided for all delegates to present a poster outlining their area of interest.

You will be expected to make your own arrangements for travel and accommodation and meet these costs.  A number of rooms at Broadview Lodge (University of East Anglia campus) and The Maids Head hotel in Norwich city centre have been reserved at a reduced rate, but as these are limited so please book early to avoid disappointment (see ‘More Info’ tab on below registration link for further details).

To register for this event and book to attend the dinner, please follow this link: https://payments.liv.ac.uk/conferences-and-events/events-at-liverpool/institute-of-infection-and-global-health/vectorborne-diseases-in-the-uk-vbd2018. Registering to attend the meeting will close on the 11thNovember, with Abstract submissions closing on the 13th August.

Further details on all topics associated with this meeting can be obtained from the meeting organisers at livvec@liverpool.ac.uk, or you can visithttp://www.hpruezi.nihr.ac.uk/about-us/news-and-events/vbd-uk-2018/

ZSL Symposium on Amphibian Pathogens

Mitigating single pathogen and co-infections that threaten amphibian biodiversity

24 Apr – 25 Apr 2019

Zoological Society of London, Regents Park, London. 

Amphibians continue to experience worldwide declines and remain the most threatened vertebrate class. Nearly 30 years of research has shown that pathogens, in particular chytridiomycete fungi and ranaviruses, are responsible for infectious diseases that cause catastrophic population and host community declines on all continents where amphibians exist. While our understanding of the conditions required for amphibian-host decline has grown significantly, our ability to convert this knowledge into practical strategies for managing amphibian pathogens lags far behind. In contrast, the pathogens are moving quickly, and beginning to emerge as mixed infections, causing even greater declines.

This two-day symposium is the first international event to approach chytrids and ranaviruses as a combined threat to amphibians. It will drawn on key research communities, as well as on-the-ground conservationists, to aid the process of moving beyond single pathogen research and management, into managing mixed infections and potentially competing pathogens. Speakers will outline the conservation issues amphibians face and how disease figures in these, provide background on the threat posed by single versus mixed pathogen dynamics, and the outcomes of field mitigation strategies. This symposium will bring together the amphibian research and conservation communities to develop 21st century strategies for combating rapidly emerging mixed infections that are already threatening global amphibian biodiversity.

For more information on this event, visit this link.

Hydra Conference on Parasitic Helminths – New Perspectives in Biology and Infection

We are pleased to announce that the Hydra Conference on Parasitic Helminths - New Perspectives in Biology and Infection, at the Bratsera Hotel, Hydra, Greece, will be held from 1 to 6 September 2019.  After 12 successful meetings under the banner of Molecular and Cellular Biology of Helminth Parasites, the Conference has a new name, but will keep its special atmosphere of cutting-edge science and extensive discussion within a small meeting format.  We are also returning to the same beautiful venue that has hosted the Conference since 2002, and the meeting is being co-organised by Richard E. Davis, Niki Gounaris, Rick Maizels and Murray Selkirk.

The conference will begin on the evening of Sunday 1 September, and run through until the evening of Thursday 5 September; delegates will depart on the morning of Friday 6 September.  As in previous meetings, most presentations will be selected from submitted Abstracts in themed sessions, together with an exciting set of invited speakers representing helminth research from around the world:

Alejandro Sanchez Alvarado  (Keynote), Stowers Institute for Medical Research, Wellington, Kansas City, USA

Amy Buck, Institute for Immunology and Infection, University of Edinburgh, UK

Luisa Cochella, Institute for Molecular Pathology, Vienna, Austria

Alison Elliott, MRC Uganda Virus Institute, Entebbe, Uganda

Carolina Escobar, University of Castilla La Mancha, Toledo, Spain

Elodie Ghedin, Center for Genomics and Systems Biology, New York University, USA

Nicola Harris, Immunology and Pathology, Monash University, Melbourne, Australia

Karl Hoffmann, Aberystwyth University, UK

P'ng Loke, Department of Microbiology (Parasitology), New York University, USA

Peter Sarkies, MRC London Institute for Medical Sciences, Imperial College London, UK

William Sullivan, Molecular, Cell and Developmental Biology, University of California Santa Cruz, USA

In 2019, the Conference will include a special Mini-Symposium on Small RNAs combining both invited speakers and talks chosen from Abstracts. In addition there will be around 40 oral presentations selected from the Abstracts, and a similar number of Posters; the poster sessions are kept to a limited size and all presenters give a 2-minute "Poster Pitch" to the whole conference immediately before the session, which has proven an excellent formula to maximise interest in every poster.

We will be extending the period for registration on the Conference website, http://hydra.bio.ed.ac.uk, to start from Monday 14 January 2019.  The closing date for registration will be Friday 29 March.

As capacity of the meeting is limited to 100 participants, please await confirmation before making travel arrangements. In case of over-subscription, places will be allocated on the basis of abstracts. Confirmation of participation will be sent shortly after the closing date. The registration fee (which includes all events, refreshments, some evening meals etc) will be announced shortly prior to registration. No payment will be required prior to confirmation.

We would also like to draw attention to our Bursary scheme which will cover costs for a small number of younger scientists from Africa, Asia and Latin America to attend the Conference.

We will be pleased to answer any questions if you contact us on Hydra@ed.ac.uk.

Finally, we are delighted that from 2019 two great new investigators will join the Hydra Organising Committee, Dr Amy Buck (University of Edinburgh, UK), and Dr Jim Collins (University of Texas Southwestern Medical Center, Dallas, USA). Please feel free to contact any of us with comments or suggestions about the Conference.

We're sure that this will be another exciting and enjoyable meeting, with the same informal and interactive atmosphere as in previous years. We look forward to seeing you there!

Richard E. Davis, Niki Gounaris, Rick Maizels, Murray Selkirk

Wellcome Centre Anti-Infectives Research Conference

WCAIR_Conference_web_872x340

Venue

University of Dundee

Dates

12 - 15 May 2019

 

The first conference of the Wellcome Centre for Anti-Infectives Research aims to harness cross-disciplinary and cross-disease learning to accelerate drug discovery and reduce drug candidate attrition rates for infectious diseases affecting low and middle income countries. Conference attendees will take home new ideas and technologies which have been demonstrated to work; applying them to diseases where challenges to drug discovery are hampering progress.

The conference has been formatted to allow active participation of all conference delegates. Each session will feature talks from internationally recognised experts followed by a panel discussion providing the opportunity for the audience to discuss the issues raised with the speakers. There will also be plenty of networking opportunities through poster sessions and evening social events.

The organising committee encourage researchers working within disease endemic countries to attend and bring their first-hand knowledge of the impact of infectious diseases to the discussions. 20 travel bursaries worth up to £1,500 are available to those coming from low and middle income countries to assist with the costs of attending the conference. Thank you to MMV, DNDi, Novartis BioMedical Research Institute and the Bill & Melinda Gates Foundation for sponsoring the travel bursaries.

Further information on registration, travel bursaries and abstract submission can be found on the conference website http://www.lifesci.dundee.ac.uk/research/events/wcair-conference-2019 .

Deadlines

Abstract Submission

Short-talks: 31st October 2018

Posters: 31st December 2018

Registration

Early Bird, closes 30th November 2018: £300

Registration from 1st December 2018: £375

Registration closes: 5th April 2019

Invited Speakers

Bree Aldridge, Tufts University, Boston; Clif Barry, National Institute of Allergy and Infectious Diseases, Bethesda; Manu De Rycker, University of Dundee; Natalie Gobeau, Medicines for Malaria Venture; Paul Herrling; Jennifer Keiser, Swiss Tropical and Public Health Institute; Paul Leeson, Medicinal Chemistry Consultant; Didier Leroy, Medicines for Malaria Venture; James McCarthy, QIMR Berghofer Medical Research Institute, Brisbane; Valerie Mizrahi, University of Cape Town; John Overington, Medicines Discovery Catapult; John Pottage, ViiV Healthcare; Isabela  Ribeiro, Drugs for Neglected Diseases initiative; Lynn Silver, Anti-bacterial consultant; Thomas Spangenberg, Merck Global Health Institute; Shyam Sundar, Banaras Hindu University, Varanasi; Wesley Van Voorhis, University of Washington; Sir Nicholas White, Mahidol University, Thailand and Oxford University, UK; Susan Wyllie, University of Dundee.

 

Follow @WCAIRDundee #SOSID2019 for latest information on the conference.